The Journal of Allergy and Clinical Immunology
Volume 111, Issue 1 , Pages 79-86 , January 2003

A comparison of the airway response to segmental antigen bronchoprovocation in atopic asthma and allergic rhinitis

Received 14 June 2002 ,Revised 28 September 2003 ,Accepted 4 October 2002.

References 

  1. Simons FE. Allergic rhinobronchitis: the asthma-allergic rhinitis link. J Allergy Clin Immunol. 1999;104:534–540
  2. Togias AG. Systemic immunologic and inflammatory aspects of allergic rhinitis. J Allergy Clin Immunol. 2000;106:S247–S250
  3. American Thoracic Society Workshop . Immunobiology of asthma and rhinitis. Pathogenic factors and therapeutic options. Am J Respir Crit Care Med. 1999;160:1778–1787
  4. Crimi E, Milanese M, Oddera S, Mereu C, Rossi GA, Riccio A, et al.  Inflammatory and mechanical factors of allergen-induced bronchoconstriction in mild asthma and rhinitis. J Appl Physiol. 2001;91:1029–1034
  5. Shaver J, O'Connor J, Pollice M, Cho SK, Kane G, Fish J, et al.  Pulmonary inflammation after segmental ragweed challenge in allergic asthmatic and nonasthmatic subjects. Am J Respir Crit Care Med. 1995;152:1189–1197
  6. Zangrilli JG, Shaver JR, Cirelli RA, Cho SK, Garlisi CG, Falcone A, et al.  sVCAM-1 levels after segmental antigen challenge correlate with eosinophil influx, IL-4 and IL-5 production, and the late phase response. Am J Respir Crit Care Med. 1995;151:1346–1353
  7. Calhoun WJ, Jarjour NN, Gleich GJ, Stevens CA, Busse WW. Increased airway inflammation with segmental versus aerosol antigen challenge. Am Rev Respir Dis. 1993;147:1465–1471
  8. Moore WC, Hasday JD, Meltzer SS, Wisnewski PL, White B, Bleecker ER. Subjects with mild and moderate asthma respond to segmental allergen challenge with similar, reproducible, allergen-specific inflammation. J Allergy Clin Immunol. 2001;108:908–914
  9. American Thoracic Society . Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Am Rev Respir Dis. 1987;136:225–244
  10. Standardization of Spirometry, 1994 Update . American Thoracic Society. Am J Respir Crit Care Med. 1995;152:1107–1136
  11. Guidelines for methacholine and exercise challenge testing by ATS Committee on proficiency standards for clinical pulmonary function laboratories. Am J Respir Crit Care Med. 1999;161:309–329
  12. Chai H, Farr R, Froelich LA. Standardization of bronchial inhalation challenge procedures. J Allergy Clin Immunol. 1975;56:323–327
  13. Kelly EA, Rodriguez RR, Busse WW, Jarjour NN. The effect of segmental bronchoprovocation with allergen on airway lymphocyte function. Am J Respir Crit Care Med. 1997;156:1421–1428
  14. Bowsher RR, Verburg KM, Henry DP. Rat histamine N-methyltransferase. Quantification, tissue distribution, purification, and immunological properties. J Biol Chem. 1983;258:12215–12220
  15. Meerschaert JA, Kelly EA, Mosher DF, Busse WW, Jarjour NN. Segmental antigen challenge increases fibronectin in bronchoalveolar lavage fluid. Am J Respir Crit Care Med. 1999;159:619–625
  16. Alvarez MJ, Olaguibel JM, Garcia BE, Tabar AI, Urbiola E. Comparison of allergen-induced changes in bronchial hyperresponsiveness and airway inflammation between mildly allergic asthma patients and allergic rhinitis patients. Allergy. 2000;55:531–539
  17. Ndukwu IM, Naureckas ET, Maxwell C, Waldman M, Leff AR. Relationship of cellular transmigration and airway response after allergen challenge. Am J Respir Crit Care Med. 1999;160:1516–1524

☆ Supported by National Institutes of Health grant RO1 64066, an institutional Specialized Center of Research grant (NIH HL56396), and the American Lung Association of Wisconsin.

☆☆ Reprint requests: Elizabeth A. Becky Kelly, PhD, Section of Pulmonary and Critical Care Medicine, 600 Highland Ave, CSC K4/928, University of Wisconsin School of Medicine, Madison, WI 53792.

PII: S0091-6749(02)91290-X

doi: 10.1067/mai.2003.28

The Journal of Allergy and Clinical Immunology
Volume 111, Issue 1 , Pages 79-86 , January 2003

Article Tools

* Image Usage & Resolution