The Journal of Allergy and Clinical Immunology
Volume 111, Issue 1 , Pages 72-78 , January 2003

Increased oxidative stress and altered levels of antioxidants in asthma

Received 15 April 2002 ,Revised 9 September 2002 ,Accepted 26 September 2002.

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    Superoxide anion generation in leukocytes expressed as nanomoles of O2− produced per 15 minutes per 2.5 million cells. ***P < .001.

    Superoxide anion generation in leukocytes expressed as nanomoles of O2− produced per 15 minutes per 2.5 million cells. ***P < .001.

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    Lipid peroxides and total protein carbonyls in plasma expressed as micromoles of TBARS per liter and nanomoles per milligram of protein, respectively. ***P < .001.

    Lipid peroxides and total protein carbonyls in plasma expressed as micromoles of TBARS per liter and nanomoles per milligram of protein, respectively. ***P < .001.

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    NOx in plasma expressed as micromoles of NOx per liter. ***P < .001.

    NOx in plasma expressed as micromoles of NOx per liter. ***P < .001.

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    Total blood glutathione and total protein sulfhydrils in plasma expressed as millimoles per liter. *P < .05; **P < .01.

    Total blood glutathione and total protein sulfhydrils in plasma expressed as millimoles per liter. *P < .05; **P < .01.

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    Red blood cell SOD and catalase activity expressed as units per gram of hemoglobin. **P < .01; ns, P > .05.

    Red blood cell SOD and catalase activity expressed as units per gram of hemoglobin. **P < .01; ns, P > .05.

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    GSH-Px activity in red blood cells (RBC) and leukocytes expressed as micromoles of the reduced form of nicotinamide adenine dinucleotide phosphate oxidized per minute per gram of hemoglobin and nanomo

    GSH-Px activity in red blood cells (RBC) and leukocytes expressed as micromoles of the reduced form of nicotinamide adenine dinucleotide phosphate oxidized per minute per gram of hemoglobin and nanomoles of the reduced form of nicotinamide adenine dinucleotide phosphate oxidized per minute per 0.5 million cells, respectively. *P < .05; ***P < .001.

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    Ferric reducing antioxidant power in plasma expressed as micromoles per liter. ns, P > .05.

    Ferric reducing antioxidant power in plasma expressed as micromoles per liter. ns, P > .05.

☆ Ahmed Nadeem is the recipient of a Junior Research Fellowship from the Council of Scientific and Industrial Research (CSIR).

☆☆ Reprint requests: Sunil K. Chhabra, MD, Department of Cardiorespiratory Physiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi - 110 007, India.

PII: S0091-6749(02)91279-0

doi: 10.1067/mai.2003.17

The Journal of Allergy and Clinical Immunology
Volume 111, Issue 1 , Pages 72-78 , January 2003

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