Current Issue January 2012, Vol. 129, No. 1
Featured Article of the Week
Patients with X-linked agammaglobulinemia have hyperinflammatory Toll-like receptor responses Mutations in the cytoplasmic enzyme tyrosine kinase Bruton tyrosine kinase (Btk) lead to the primary immune deficiency Bruton X-linked agammaglobulinemia (XLA). Although this kinase is essential for B-cell survival, it is found in other cells as well, although with unclear function. In the past decade, Btk has also been shown to be an integral member of signaling pathways downstream from a number of Toll-like receptors (TLRs).
View all Featured Articles for this month.
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Specific allergen concentration of WHO and FDA reference preparations measured using a multiple allergen standard27 January 2012
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High sensitivity of CAP-FEIA rVes v 5 and rVes v 1 for diagnosis of Vespula venom allergy27 January 2012
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Screening for severe combined immunodeficiency in newborns27 January 2012
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CD21 deficiency, complement, and the development of common variable immunodeficiency27 January 2012
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The relationship between combination inhaled corticosteroid and long-acting β-agonist use and severe asthma exacerbations in a diverse population27 January 2012
Special Features
Shared Science. In collaboration with other journals and their sponsoring societies, the JACI is pleased to offer free online access to selected articles.
JACI in the News. View coverage of JACI articles in news outlets from around the world.
Advances in Allergy and Immunology. Our annual series reviewing the best and most exciting research reported in JACI during the previous year.
News Beyond Our Pages. Drs. Marc Rothenberg and Jean Bousquet bring you the latest in news, ideas, and research for the allergist-immunologist.
